CVE catalog

CVE-2022-46280

openbabel: CVE-2022-46280

Severity: Critical · CVSS 9.8CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H
Published: Jun 2, 2026, 12:00:00 AM UTC
Source: [NVD] · [CVE record]
EPSS: 0.83% · Oct 25, 2026

A use of uninitialized pointer vulnerability exists in the PQS format pFormat functionality of Open Babel 3.1.1 and master commit 530dbfa3. A specially crafted malformed file can lead to arbitrary code execution. An attacker can provide a malicious file to trigger this vulnerability.

Vulnerable and fixed packages

Distribution-reported package versions and fixes. These do not depend on matching against the OpenFactory package catalog.

Distribution	Package	Release	Version	Status
Debian	openbabel	sid	`3.2.0+dfsg-2`	vulnerable
Debian	openbabel	forky	`3.2.0+dfsg-1`	vulnerable
Debian	openbabel	trixie	`3.1.1+dfsg-12`	vulnerable
Debian	openbabel	bookworm	`3.1.1+dfsg-9`	vulnerable

Fixed-version evidence

Distribution	Package	Type	Release	Fixed version	Urgency	Origin	Bugs
Debian	openbabel	source	sid	`(unfixed)`	not yet assigned	Not reported	[1059277]
Debian	openbabel	source	forky	`(unfixed)`	not yet assigned	Not reported	[1059277]
Debian	openbabel	source	trixie	`(unfixed)`	not yet assigned	Not reported	[1059277]
Debian	openbabel	source	bookworm	`(unfixed)`	not yet assigned	Not reported	[1059277]

[Debian bug #1059277]

Notes

[trixie] openbabel: Minor issue, revisit when fixed upstream [bookworm] openbabel: Minor issue, revisit when fixed upstream

OpenFactory catalog packages

[Debian 12 (Bookworm)]

[libchemistry-openbabel-perl]Affected
Source package: [openbabel]
Details (2)
- 3.1.1+dfsg-9+b3 · amd64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
- 3.1.1+dfsg-9+b3 · arm64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
[libopenbabel7]Affected
Source package: [openbabel]
Details (2)
- 3.1.1+dfsg-9+b3 · amd64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
- 3.1.1+dfsg-9+b3 · arm64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
[libopenbabel-dev]Affected
Source package: [openbabel]
Details (2)
- 3.1.1+dfsg-9+b3 · amd64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
- 3.1.1+dfsg-9+b3 · arm64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
[libopenbabel-doc]Affected
Source package: [openbabel]
Details (2)
- 3.1.1+dfsg-9 · all · bookworm
  Affected
  dsa · openbabel · debian · bookworm
- 3.1.1+dfsg-9 · all · bookworm
  Affected
  dsa · openbabel · debian · bookworm
[openbabel]Affected
Source package: [openbabel]
Details (2)
- 3.1.1+dfsg-9+b3 · amd64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
- 3.1.1+dfsg-9+b3 · arm64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
[openbabel-gui]Affected
Source package: [openbabel]
Details (2)
- 3.1.1+dfsg-9+b3 · amd64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
- 3.1.1+dfsg-9+b3 · arm64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
[python3-openbabel]Affected
Source package: [openbabel]
Details (2)
- 3.1.1+dfsg-9+b3 · amd64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm
- 3.1.1+dfsg-9+b3 · arm64 · bookworm
  Affected
  dsa · openbabel · debian · bookworm

Observed: Oct 23, 2026, 6:30:49 PM UTC

References

[Debian Security Tracker] · [FIRST EPSS] · [SUSE security advisories and VEX]