CVE catalog

CVE-2025-68463

python-biopython: CVE-2025-68463

Severity: High · CVSS 7.1CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:H/I:N/A:L
Published: Dec 18, 2025, 5:40:36 AM UTC
Source: [NVD] · [CVE record]
EPSS: 0.32% · Oct 25, 2026

Bio.Entrez in Biopython through 186 allows doctype XXE.

Vulnerable and fixed packages

Distribution-reported package versions and fixes. These do not depend on matching against the OpenFactory package catalog.

Distribution	Package	Release	Version	Status
Debian	python-biopython	sid	`1.88+dfsg-2`	fixed
Debian	python-biopython	forky	`1.88+dfsg-2`	fixed
Debian	python-biopython	trixie	`1.85+dfsg-4`	vulnerable
Debian	python-biopython	bookworm	`1.80+dfsg-4`	vulnerable
Opensuse	python-biopython	leap 16.0	`1.85-bp160.2.1`	fixed
Opensuse	python-biopython	tumbleweed	`1.87-1.1`	fixed

Fixed-version evidence

Distribution	Package	Type	Release	Fixed version	Urgency	Origin	Bugs
Debian	python-biopython	source	sid	`1.87+dfsg-1`	not yet assigned	Not reported	[1123673]
Debian	python-biopython	source	forky	`1.87+dfsg-1`	not yet assigned	Not reported	[1123673]
Debian	python-biopython	source	trixie	`(unfixed)`	not yet assigned	Not reported	[1123673]
Debian	python-biopython	source	bookworm	`(unfixed)`	not yet assigned	Not reported	[1123673]
Opensuse	python-biopython	rpm	leap 16.0	`1.85-bp160.2.1`	Not reported	OPENSUSE-SU-2026:21169-1	Not reported
Opensuse	python-biopython	rpm	tumbleweed	`1.87-1.1`	Not reported	OPENSUSE-SU-2026:10537-1	Not reported

[Debian bug #1123673]

Notes

[trixie] python-biopython: Minor issue [bookworm] python-biopython: Minor issue

OpenFactory catalog packages

[Debian 12 (Bookworm)]

[python3-biopython]Affected
Source package: [python-biopython]
Details (2)
- 1.80+dfsg-4+b1 · amd64 · bookworm
  Affected
  dsa · python-biopython · debian · bookworm
- 1.80+dfsg-4+b1 · arm64 · bookworm
  Affected
  dsa · python-biopython · debian · bookworm
[python3-biopython-sql]Affected
Source package: [python-biopython]
Details (2)
- 1.80+dfsg-4 · all · bookworm
  Affected
  dsa · python-biopython · debian · bookworm
- 1.80+dfsg-4 · all · bookworm
  Affected
  dsa · python-biopython · debian · bookworm
[python-biopython-doc]Affected
Source package: [python-biopython]
Details (2)
- 1.80+dfsg-4 · all · bookworm
  Affected
  dsa · python-biopython · debian · bookworm
- 1.80+dfsg-4 · all · bookworm
  Affected
  dsa · python-biopython · debian · bookworm

[openSUSE Tumbleweed]

[python313-biopython]Unknown
Source package: [python-biopython]
Details (1)
- 1.88-1.1 · x86_64 · tumbleweed
  Unknown · Fixed: 1.87-1.1
  Version impact unknown
  dsa · python-biopython · opensuse · tumbleweed
[python314-biopython]Unknown
Source package: [python-biopython]
Details (1)
- 1.88-1.1 · x86_64 · tumbleweed
  Unknown · Fixed: 1.87-1.1
  Version impact unknown
  dsa · python-biopython · opensuse · tumbleweed

Observed: Oct 24, 2026, 8:00:22 AM UTC

References

[Debian Security Tracker] · [FIRST EPSS] · [National Vulnerability Database (NVD)] · [OSV Package Vulnerability Database] · [Red Hat security advisories and VEX] · [SUSE security advisories and VEX]