CVE catalog

CVE-2026-31962

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. While most alignment records store DNA sequence and quali

[CVE catalog]

Severity
High · CVSS 8.8
Published
Source
[NVD] · [CVE record]
EPSS
0.38% · Oct 25, 2026

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. While most alignment records store DNA sequence and quality values, the format also allows them to omit this data in certain cases to save space. Due to some quirks of the CRAM format, it is necessary to handle these records carefully as they will actually store data that needs to be consumed and then discarded. Unfortunately the `cram_decode_seq()` did not handle this correctly in some cases. Where this happened it could result in reading a single byte from beyond the end of a heap allocation, followed by writing a single attacker-controlled byte to the same location. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Vulnerable and fixed packages

Distribution-reported package versions and fixes. These do not depend on matching against the OpenFactory package catalog.

DistributionPackageReleaseVersionStatus
Debianhtslibsid1.24-3fixed
Debianhtslibforky1.24-3fixed
Debianhtslibtrixie1.21+ds-1vulnerable
Debianhtslibbookworm1.16+ds-3vulnerable
CpehtslibNot reportedNot reportedvulnerable

Fixed-version evidence

DistributionPackageTypeReleaseFixed versionUrgencyOriginBugs
Debianhtslibsourcesid1.24-2not yet assignedNot reported[1131493]
Debianhtslibsourceforky1.24-2not yet assignedNot reported[1131493]
Debianhtslibsourcetrixie(unfixed)not yet assignedNot reported[1131493]
Debianhtslibsourcebookworm(unfixed)not yet assignedNot reported[1131493]

[Debian bug #1131493]

Notes

[trixie] htslib: Minor issue [bookworm] htslib: Minor issue

OpenFactory catalog packages

[Debian 12 (Bookworm)]

  • [htslib-test]Affected

    Source package: [htslib]

    Details (2)
    • 1.16+ds-3 · all · bookworm

      Affected

      nvd · htslib · debian · bookworm; nvd · htslib · debian · 12

    • 1.16+ds-3 · all · bookworm

      Affected

      nvd · htslib · debian · bookworm; nvd · htslib · debian · 12

  • [libhts3]Affected

    Source package: [htslib]

    Details (2)
    • 1.16+ds-3 · amd64 · bookworm

      Affected

      nvd · htslib · debian · bookworm; nvd · htslib · debian · 12

    • 1.16+ds-3 · arm64 · bookworm

      Affected

      nvd · htslib · debian · bookworm; nvd · htslib · debian · 12

  • [libhts-dev]Affected

    Source package: [htslib]

    Details (2)
    • 1.16+ds-3 · amd64 · bookworm

      Affected

      nvd · htslib · debian · bookworm; nvd · htslib · debian · 12

    • 1.16+ds-3 · arm64 · bookworm

      Affected

      nvd · htslib · debian · bookworm; nvd · htslib · debian · 12

  • [tabix]Affected

    Source package: [htslib]

    Details (2)
    • 1.16+ds-3 · amd64 · bookworm

      Affected

      nvd · htslib · debian · bookworm; nvd · htslib · debian · 12

    • 1.16+ds-3 · arm64 · bookworm

      Affected

      nvd · htslib · debian · bookworm; nvd · htslib · debian · 12

[Debian 13 (Trixie)]

  • [htslib-test]Affected

    Source package: [htslib]

    Details (2)
    • 1.21+ds-1 · all · trixie

      Affected

      nvd · htslib · debian · 13

    • 1.21+ds-1 · all · trixie

      Affected

      nvd · htslib · debian · 13

  • [libhts3t64]Affected

    Source package: [htslib]

    Details (2)
    • 1.21+ds-1 · amd64 · trixie

      Affected

      nvd · htslib · debian · 13

    • 1.21+ds-1 · arm64 · trixie

      Affected

      nvd · htslib · debian · 13

  • [libhts-dev]Affected

    Source package: [htslib]

    Details (2)
    • 1.21+ds-1 · amd64 · trixie

      Affected

      nvd · htslib · debian · 13

    • 1.21+ds-1 · arm64 · trixie

      Affected

      nvd · htslib · debian · 13

  • [tabix]Affected

    Source package: [htslib]

    Details (2)
    • 1.21+ds-1 · amd64 · trixie

      Affected

      nvd · htslib · debian · 13

    • 1.21+ds-1 · arm64 · trixie

      Affected

      nvd · htslib · debian · 13

Observed:

References