
CVE catalog
CVE-2026-31963
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. As one method of removing redundant data, CRAM uses refer
- Severity
- High · CVSS 8.8
- Published
- Source
- [NVD] · [CVE record]
- EPSS
- 0.36% · Oct 25, 2026
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. As one method of removing redundant data, CRAM uses reference-based compression so that instead of storing the full sequence for each alignment record it stores a location in an external reference sequence along with a list of differences to the reference at that location as a sequence of "features". When decoding these features, an out-by-one error in a test for CRAM features that appear beyond the extent of the CRAM record sequence could result in an invalid write of one attacker-controlled byte beyond the end of a heap buffer. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
Vulnerable and fixed packages
Distribution-reported package versions and fixes. These do not depend on matching against the OpenFactory package catalog.
| Distribution | Package | Release | Version | Status |
|---|---|---|---|---|
| Debian | htslib | sid | 1.24-3 | fixed |
| Debian | htslib | forky | 1.24-3 | fixed |
| Debian | htslib | trixie | 1.21+ds-1 | vulnerable |
| Debian | htslib | bookworm | 1.16+ds-3 | vulnerable |
| Cpe | htslib | Not reported | Not reported | vulnerable |
| Cpe | htslib | Not reported | Not reported | unknown |
Fixed-version evidence
| Distribution | Package | Type | Release | Fixed version | Urgency | Origin | Bugs |
|---|---|---|---|---|---|---|---|
| Debian | htslib | source | sid | 1.24-2 | not yet assigned | Not reported | [1131493] |
| Debian | htslib | source | forky | 1.24-2 | not yet assigned | Not reported | [1131493] |
| Debian | htslib | source | trixie | (unfixed) | not yet assigned | Not reported | [1131493] |
| Debian | htslib | source | bookworm | (unfixed) | not yet assigned | Not reported | [1131493] |
Notes
[trixie] htslib: Minor issue [bookworm] htslib: Minor issue
OpenFactory catalog packages
[Debian 12 (Bookworm)]
- [htslib-test]Affected
Source package: [htslib]
Details (2)
1.16+ds-3· all · bookwormAffected
nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
1.16+ds-3· all · bookwormAffected
nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
- [libhts3]Affected
Source package: [htslib]
Details (2)
1.16+ds-3· amd64 · bookwormAffected
nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
1.16+ds-3· arm64 · bookwormAffected
nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
- [libhts-dev]Affected
Source package: [htslib]
Details (2)
1.16+ds-3· amd64 · bookwormAffected
nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
1.16+ds-3· arm64 · bookwormAffected
nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
- [tabix]Affected
Source package: [htslib]
Details (2)
1.16+ds-3· amd64 · bookwormAffected
nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
1.16+ds-3· arm64 · bookwormAffected
nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
[Debian 13 (Trixie)]
- [htslib-test]Affected
Source package: [htslib]
Details (2)
1.21+ds-1· all · trixieAffected
nvd · htslib · debian · 13
1.21+ds-1· all · trixieAffected
nvd · htslib · debian · 13
- [libhts3t64]Affected
Source package: [htslib]
Details (2)
1.21+ds-1· amd64 · trixieAffected
nvd · htslib · debian · 13
1.21+ds-1· arm64 · trixieAffected
nvd · htslib · debian · 13
- [libhts-dev]Affected
Source package: [htslib]
Details (2)
1.21+ds-1· amd64 · trixieAffected
nvd · htslib · debian · 13
1.21+ds-1· arm64 · trixieAffected
nvd · htslib · debian · 13
- [tabix]Affected
Source package: [htslib]
Details (2)
1.21+ds-1· amd64 · trixieAffected
nvd · htslib · debian · 13
1.21+ds-1· arm64 · trixieAffected
nvd · htslib · debian · 13
Observed:
References
- [https://nvd.nist.gov/vuln/detail/CVE-2026-31963]
- [https://osv.dev/vulnerability/DEBIAN-CVE-2026-31963]
- [https://security-tracker.debian.org/tracker/CVE-2026-31963]
- [https://security.access.redhat.com/data/csaf/v2/vex/2026/cve-2026-31963.json]
[Debian Security Tracker] · [FIRST EPSS] · [National Vulnerability Database (NVD)] · [OSV Package Vulnerability Database] · [Red Hat security advisories and VEX]