CVE catalog

CVE-2026-31964

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. Whi

[CVE catalog]

Severity: Medium · CVSS 6.9
Published: Mar 18, 2026, 6:27:26 PM UTC
Source: [NVD] · [CVE record]
EPSS: 0.34% · Oct 25, 2026

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. While most alignment records store DNA sequence and quality values, the format also allows them to omit this data in certain cases to save space. Due to some quirks of the CRAM format, it is necessary to handle these records carefully as they will actually store data that needs to be consumed and then discarded. Unfortunately the `CONST`, `XPACK` and `XRLE` encodings did not properly implement the interface needed to do this. Trying to decode records with omitted sequence or quality data using these encodings would result in an attempt to write to a NULL pointer. Exploiting this bug causes a NULL pointer dereference. Typically this will cause the program to crash. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Vulnerable and fixed packages

Distribution-reported package versions and fixes. These do not depend on matching against the OpenFactory package catalog.

Distribution	Package	Release	Version	Status
Debian	htslib	sid	`1.24-3`	fixed
Debian	htslib	forky	`1.24-3`	fixed
Debian	htslib	trixie	`1.21+ds-1`	vulnerable
Debian	htslib	bookworm	`1.16+ds-3`	vulnerable
Cpe	htslib	Not reported	Not reported	vulnerable
Cpe	htslib	Not reported	Not reported	unknown

Fixed-version evidence

Distribution	Package	Type	Release	Fixed version	Urgency	Origin	Bugs
Debian	htslib	source	sid	`1.24-2`	not yet assigned	Not reported	[1131493]
Debian	htslib	source	forky	`1.24-2`	not yet assigned	Not reported	[1131493]
Debian	htslib	source	trixie	`(unfixed)`	not yet assigned	Not reported	[1131493]
Debian	htslib	source	bookworm	`(unfixed)`	not yet assigned	Not reported	[1131493]

[Debian bug #1131493]

Notes

[trixie] htslib: Minor issue [bookworm] htslib: Minor issue

OpenFactory catalog packages

[Debian 12 (Bookworm)]

[htslib-test]Affected
Source package: [htslib]
Details (2)
- 1.16+ds-3 · all · bookworm
  Affected
  nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
- 1.16+ds-3 · all · bookworm
  Affected
  nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
[libhts3]Affected
Source package: [htslib]
Details (2)
- 1.16+ds-3 · amd64 · bookworm
  Affected
  nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
- 1.16+ds-3 · arm64 · bookworm
  Affected
  nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
[libhts-dev]Affected
Source package: [htslib]
Details (2)
- 1.16+ds-3 · amd64 · bookworm
  Affected
  nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
- 1.16+ds-3 · arm64 · bookworm
  Affected
  nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
[tabix]Affected
Source package: [htslib]
Details (2)
- 1.16+ds-3 · amd64 · bookworm
  Affected
  nvd · htslib · debian · bookworm; nvd · htslib · debian · 12
- 1.16+ds-3 · arm64 · bookworm
  Affected
  nvd · htslib · debian · bookworm; nvd · htslib · debian · 12

[Debian 13 (Trixie)]

[htslib-test]Affected
Source package: [htslib]
Details (2)
- 1.21+ds-1 · all · trixie
  Affected
  nvd · htslib · debian · 13
- 1.21+ds-1 · all · trixie
  Affected
  nvd · htslib · debian · 13
[libhts3t64]Affected
Source package: [htslib]
Details (2)
- 1.21+ds-1 · amd64 · trixie
  Affected
  nvd · htslib · debian · 13
- 1.21+ds-1 · arm64 · trixie
  Affected
  nvd · htslib · debian · 13
[libhts-dev]Affected
Source package: [htslib]
Details (2)
- 1.21+ds-1 · amd64 · trixie
  Affected
  nvd · htslib · debian · 13
- 1.21+ds-1 · arm64 · trixie
  Affected
  nvd · htslib · debian · 13
[tabix]Affected
Source package: [htslib]
Details (2)
- 1.21+ds-1 · amd64 · trixie
  Affected
  nvd · htslib · debian · 13
- 1.21+ds-1 · arm64 · trixie
  Affected
  nvd · htslib · debian · 13

Observed: Oct 23, 2026, 10:40:20 PM UTC

References

[Debian Security Tracker] · [FIRST EPSS] · [National Vulnerability Database (NVD)] · [OSV Package Vulnerability Database] · [Red Hat security advisories and VEX]